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DIM +
Cleaner estrogen metabolism. The classic perimenopause adjunct — and the most-asked-about bottle on this shelf.
What it does.
DIM (3,3'-diindolylmethane) is the metabolite the body produces from cruciferous vegetables — the one that nudges estrogen down the cleaner 2-hydroxy pathway. We dose it at 200mg, paired with calcium-D-glucarate to support phase-II detoxification in the liver.
The patients who notice it most: women in perimenopause with cycle-related breast tenderness, mood swings, or stubborn estrogen-dominant symptoms. Two capsules with breakfast.
DIM is not a substitute for hormone replacement, and it will not fix every symptom. It does one job, and it does it well — which is why it is the bottle most often refilled on this shelf.
- Form
- Capsule
- Dose
- 2 capsules daily, with breakfast
- Quantity
- 60 capsules · 30-day supply
- Sourcing
- US-manufactured, GMP-certified
The full ingredient deck.
- DIM (3,3'-diindolylmethane) — 200mg
- Calcium-D-Glucarate — 100mg
- BioPerine (black pepper extract) — 5mg
Sample formulation · See product label for current values





