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Berman Supplements · Metabolic

Berberine +

Glucose, lipids, and gut motility — the small molecule frequently called nature's metformin.

Berberine +
Metabolic

What it does.

Berberine is a small alkaloid extracted from the goldenseal and barberry families. The literature on glucose handling, lipid profiles, and gut motility is robust enough that the molecule is sometimes called nature's metformin — which is overstated, but in the right ballpark.

I prescribe it most often for patients with insulin resistance, PCOS, mild dyslipidemia, or stubborn weight that is not responding to dietary work alone. Paired with milk thistle to support the liver clearance pathway berberine relies on.

Two capsules, twice daily, with the largest two meals. It is not a stimulant. It is a metabolic adjunct, and it works when the rest of the lifestyle work is also being done.

Form
Capsule
Dose
2 capsules twice daily, with meals
Quantity
120 capsules · 30-day supply
Sourcing
US-manufactured, GMP-certified
$80.00USD · single bottle
Free US shipping over $150
Why this exists

Working dose only.

The studied dose is 1,000–1,500mg per day, split. Most retail bottles dose at 200–500mg total, which will not move the labs. We dose at 500mg per capsule so two capsules twice daily lands in the working range.

Berberine has interactions, particularly with metformin and certain blood-pressure medications. Talk to your doctor before adding it if you are on a regimen.

What's inside

The full ingredient deck.

  • Berberine HCl — 500mg
  • Milk thistle extract (silymarin) — 200mg
  • BioPerine (black pepper extract) — 5mg

Sample formulation · See product label for current values

Also on the shelf

Often paired with this.

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WhereSecure video · your phone or laptopLength45 min consultBest forHormones, supplements, follow-ups, second opinions
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